Orthogonal Signal Correction (OSC) is a spectral preprocessing technique that removes variation from a data matrix X that is orthogonal to the response matrix Y.[1] OSC was introduced by researchers at the University of Umea in 1998 and has since found applications in domains including metabolomics.[2][3][4][5]
References
edit- ^ Wold, Svante; Antti, Henrik; Lindgren, F; Ohman, J (1998), "Orthogonal signal correction of near-infrared spectra", Chemometrics and Intelligent Laboratory Systems, 44 (1–2): 175–185, doi:10.1016/s0169-7439(98)00109-9
- ^ Mao H, Wang H, Wang B, et al. (2009). "Systemic metabolic changes of traumatic critically ill patients revealed by an NMR-based metabonomic approach". J. Proteome Res. 8 (12): 5423–30. doi:10.1021/pr900576y. PMID 19835422.
- ^ Tzovaras VT, Psychogios NG, Kostara CE, Bairaktari ET, Elisaf MS (2009). "Evaluation of the proximal tubular function in individuals with primary renal hypouricemia: an NMR-based metabonomic study". NMR Biomed. 22 (10): 1072–83. doi:10.1002/nbm.1415. PMID 19593759.
- ^ Gu H, Pan Z, Xi B, et al. (2009). "1H NMR metabolomics study of age profiling in children". NMR Biomed. 22 (8): 826–33. doi:10.1002/nbm.1395. PMC 4009993. PMID 19441074.
- ^ Brindle JT, Nicholson JK, Schofield PM, Grainger DJ, Holmes E (2003). "Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension". Analyst. 128 (1): 32–6. Bibcode:2003Ana...128...32B. doi:10.1039/b209155k. PMID 12572799.
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