Osaterone

Osaterone
Clinical data
Other names	TZP-5258; Gestoxarone; 2-Oxachloromadinone; 17α-Hydroxy-6-chloro-2-oxa-6-dehydroprogesterone; 17α-Hydroxy-6-chloro-2-oxapregna-4,6-diene-3,20-dione
Identifiers
	IUPAC name (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-5-chloro-1-hydroxy-9a,11a-dimethyl-2,3,3a,3b,9,9b,10,11-octahydroindeno[4,5-h]isochromen-7-one;
CAS Number	105149-04-0;
PubChem CID	3047806;
ChemSpider	2310122;
UNII	XPI95TLO4O;
CompTox Dashboard (EPA)	DTXSID40883157 ;
Chemical and physical data
Formula	C20H25ClO4
Molar mass	364.87 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)OC[C@]34C)Cl)C)O;
	InChI InChI=1S/C20H25ClO4/c1-11(22)20(24)7-5-14-12-8-16(21)15-9-17(23)25-10-18(15,2)13(12)4-6-19(14,20)3/h8-9,12-14,24H,4-7,10H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1; Key:ZLLOIFNEEWYATC-XMUHMHRVSA-N;

Osaterone (developmental code name TZP-5258), also known as 17α-hydroxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone, is a steroidal antiandrogen and progestin that was never marketed.^[1]^[2] The C17α acetate ester of osaterone, osaterone acetate, in contrast, has been marketed.^[1]^[2]