Osenovo may refer to:
- In Bulgaria (written in Cyrillic as Осеново):
- Osenovo, Blagoevgrad Province - a town in the Bansko municipality, Blagoevgrad Province
- Osenovo, Varna Province - a village in the Aksakovo municipality, Varna Province
- One of two villages in the Simitli municipality, Blagoevgrad Province
- Dolno Osenovo or Lower Osenovo (Долно Осеново)
- Gorno Osenovo or Upper Osenovo (Горно Осеново)