Oswell is both a surname and a given name. Notable people with the name include:
- Francis Oswell (1920–2003), Australian architect
- Jason Oswell (born 1992), English footballer
- William Cotton Oswell (1818–1893), English explorer
- Oswell Blakeston, pseudonym of Henry Joseph Hasslacher (1907–1985), British writer and artist
- Oswell Borradaile (1859–1935), English cricketer