Oxanamide

Oxanamide
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-ethyl-3-propyloxirane-2-carboxamide;
CAS Number	126-93-2;
PubChem CID	31365;
ChemSpider	29098;
UNII	050271194T;
CompTox Dashboard (EPA)	DTXSID50925350 ;
Chemical and physical data
Formula	C8H15NO2
Molar mass	157.213 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCC1C(O1)(CC)C(=O)N;
	InChI InChI=1S/C8H15NO2/c1-3-5-6-8(4-2,11-6)7(9)10/h6H,3-5H2,1-2H3,(H2,9,10); Key:WBLPIVIXQOFTPQ-UHFFFAOYSA-N;
	(verify)

Oxanamide (Quiactin) is an anxiolytic and muscle relaxant which can produce sedative and hypnotic effects in sufficiently high doses.^[1] An uncontrolled trial on patients treated in a clinical gynecology practice published in 1959 found that oxanamide was efficacious in the treatment of anxiety resulting from premenstrual syndrome, menopause, and various other causes, with minimal sedation or other side effects.^[2]

References

^ Kuhn WL, Ketteler HJ, Van Maanen EF (January 1960). "Effects of oxanamide on the central nervous system". Proceedings of the Society for Experimental Biology and Medicine. 103: 101–3. doi:10.3181/00379727-103-25425. PMID 14412594. S2CID 40927309.
^ Woodhull RB (April 1959). "Oxanamide; adjunctive use of a new tranquilizer in gynecology". California Medicine. 90 (4): 275–7. PMC 1577644. PMID 13638840.

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[1] Kuhn WL, Ketteler HJ, Van Maanen EF (January 1960). "Effects of oxanamide on the central nervous system". Proceedings of the Society for Experimental Biology and Medicine. 103: 101–3. doi:10.3181/00379727-103-25425. PMID 14412594. S2CID 40927309.

[2] Woodhull RB (April 1959). "Oxanamide; adjunctive use of a new tranquilizer in gynecology". California Medicine. 90 (4): 275–7. PMC 1577644. PMID 13638840.

[1]

[2]

Clinical data

ATC code	none
Identifiers
IUPAC name 2-ethyl-3-propyloxirane-2-carboxamide
CAS Number	126-93-2
PubChem CID	31365
ChemSpider	29098
UNII	050271194T
CompTox Dashboard (EPA)	DTXSID50925350
Chemical and physical data
Formula	C₈H₁₅NO₂
Molar mass	157.213 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCCC1C(O1)(CC)C(=O)N
InChI InChI=1S/C8H15NO2/c1-3-5-6-8(4-2,11-6)7(9)10/h6H,3-5H2,1-2H3,(H2,9,10) Key:WBLPIVIXQOFTPQ-UHFFFAOYSA-N
(verify)