P-benzoquinone reductase (NADPH)

In enzymology, a p-benzoquinone reductase (NADPH) (EC 1.6.5.6) is an enzyme that catalyzes the chemical reaction

p-benzoquinone reductase (NADPH)
Identifiers
EC no.1.6.5.6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
NADPH + H+ + p-benzoquinone NADP+ + hydroquinone

The 3 substrates of this enzyme are NADPH, H+, and p-benzoquinone, whereas its two products are NADP+ and hydroquinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is NADPH:p-benzoquinone oxidoreductase. This enzyme participates in gamma-hexachlorocyclohexane degradation.

References

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  • Spain JC, Gibson DT (1991). "Pathway for Biodegradation of p-Nitrophenol in a Moraxella sp". Appl. Environ. Microbiol. 57 (3): 812–819. PMC 182799. PMID 16348446.