Partitioning defective 3 homolog B is a protein that in humans is encoded by the PARD3B gene.[5][6][7]

PARD3B
Identifiers
AliasesPARD3B, ALS2CR19, PAR3B, PAR3L, PAR3LC, PAR3beta, Par3Lb, par-3 family cell polarity regulator beta
External IDsMGI: 1919301; HomoloGene: 35389; GeneCards: PARD3B; OMA:PARD3B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001302769
NM_057177
NM_152526
NM_205863

NM_001081050

RefSeq (protein)

NP_001289698
NP_476518
NP_689739
NP_995585

NP_001074519

Location (UCSC)Chr 2: 204.55 – 205.62 MbChr 1: 61.68 – 62.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

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PARD3B has been shown to interact with Mothers against decapentaplegic homolog 3.[8]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116117Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052062Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, Nasir J, Brown RH Jr, Scherer SW, Rouleau GA, Hayden MR, Ikeda JE (Oct 2001). "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2". Nat Genet. 29 (2): 166–73. doi:10.1038/ng1001-166. PMID 11586298. S2CID 52828189.
  6. ^ Kohjima M, Noda Y, Takeya R, Saito N, Takeuchi K, Sumimoto H (Dec 2002). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions". Biochem Biophys Res Commun. 299 (4): 641–6. doi:10.1016/S0006-291X(02)02698-0. PMID 12459187.
  7. ^ "Entrez Gene: PARD3B par-3 partitioning defective 3 homolog B (C. elegans)".
  8. ^ Warner DR, Pisano M Michele, Roberts Emily A, Greene Robert M (Mar 2003). "Identification of three novel Smad binding proteins involved in cell polarity". FEBS Lett. 539 (1–3). Netherlands: 167–73. doi:10.1016/S0014-5793(03)00155-8. ISSN 0014-5793. PMID 12650946. S2CID 7429554.

Further reading

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