PLEKHA6

Pleckstrin homology domain-containing family A member 6 is a protein that in humans is encoded by the PLEKHA6 gene.

PLEKHA6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D9Y, 2YRY
Identifiers
Aliases	PLEKHA6, PEPP-3, PEPP3, pleckstrin homology domain containing A6
External IDs	OMIM: 607771; MGI: 2388662; HomoloGene: 137310; GeneCards: PLEKHA6; OMA:PLEKHA6 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q32.1 Start 204,218,853 bp End 204,377,665 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 E4 Start 133,164,210 bp End 133,303,435 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in C1 segment Brodmann area 23 right hemisphere of cerebellum rectum middle temporal gyrus mucosa of transverse colon endothelial cell primary visual cortex right frontal lobe apex of heart Top expressed in interventricular septum spermatid neural layer of retina zygote visual cortex primary visual cortex right kidney superior frontal gyrus cerebellar cortex deep cerebellar nuclei More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 22874 240753 Ensembl ENSG00000143850 ENSMUSG00000041757 UniProt Q9Y2H5 Q7TQG1 RefSeq (mRNA) NM_014935 NM_138480 NM_001160268 NM_182930 RefSeq (protein) NP_055750 NP_001153740 NP_891846 Location (UCSC) Chr 1: 204.22 – 204.38 Mb Chr 1: 133.16 – 133.3 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Clark TA, Schweitzer AC, Chen TX, et al. (2007). "Discovery of tissue-specific exons using comprehensive human exon microarrays". Genome Biol. 8 (4): R64. doi:10.1186/gb-2007-8-4-r64. PMC 1896007. PMID 17456239.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.

External links

• Overview of all the structural information available in the PDB for UniProt: Q9Y2H5 (Pleckstrin homology domain-containing family A member 6) at the PDBe-KB.