Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene .[ 5]
POLE4 is a histone -fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[ 5]
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This article incorporates text from the United States National Library of Medicine , which is in the public domain .
