Basic salivary proline-rich protein 4 is a protein that in humans is encoded by the PRB4 gene.[3]

PRB4
Identifiers
AliasesPRB4, Po, proline-rich protein BstNI subfamily 4, proline rich protein BstNI subfamily 4
External IDsOMIM: 180990; GeneCards: PRB4; OMA:PRB4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002723
NM_001261399

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 12: 11.31 – 11.31 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

The protein encoded by this gene is a proline-rich salivary protein. This gene and five other genes that also encode salivary proline-rich proteins (PRPs), as well as a gene encoding a lacrimal gland PRP, form a PRP gene cluster in the chromosomal 12p13 region.[3]

PRB4 is post-translationally cleaved into three different mature peptides:

  • Protein N1
  • Glycosylated protein A
  • Peptide P-D (also known as proline-rich peptide IB-5)

References

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  1. ^ a b c ENSG00000230657 GRCh38: Ensembl release 89: ENSG00000274839, ENSG00000230657Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: PRB4 proline-rich protein BstNI subfamily 4".

Further reading

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