52 kDa repressor of the inhibitor of the protein kinase is an enzyme that in humans is encoded by the PRKRIR gene.[4][5]

THAP12
Identifiers
AliasesTHAP12, DAP4, P52rIPK, THAP0, PRKRIR, THAP domain containing 12
External IDsOMIM: 607374; MGI: 1920231; HomoloGene: 37952; GeneCards: THAP12; OMA:THAP12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004705

NM_028410
NM_001355114

RefSeq (protein)

NP_004696

NP_082686
NP_001342043

Location (UCSC)n/aChr 7: 98.35 – 98.37 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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PRKRIR has been shown to interact with STK4[6] and DNAJC3.[4]

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030753Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ a b Gale M Jr; Blakely CM; Hopkins DA; Melville MW; Wambach M; Romano PR; Katze MG (Feb 1998). "Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK". Mol Cell Biol. 18 (2): 859–71. doi:10.1128/mcb.18.2.859. PMC 108797. PMID 9447982.
  5. ^ "Entrez Gene: PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)".
  6. ^ Lin, Yenshou; Khokhlatchev Andrei; Figeys Daniel; Avruch Joseph (Dec 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". J. Biol. Chem. 277 (50). United States: 47991–8001. doi:10.1074/jbc.M202630200. ISSN 0021-9258. PMID 12384512.

Further reading

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