Pre-mRNA-processing factor 19 is a protein that in humans is encoded by the PRPF19 gene.[5][6]

PRPF19
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPRPF19, NMP200, PRP19, PSO4, SNEV, UBOX4, hPSO4, pre-mRNA processing factor 19
External IDsOMIM: 608330; MGI: 106247; HomoloGene: 6421; GeneCards: PRPF19; OMA:PRPF19 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014502

NM_001253843
NM_001253844
NM_134129

RefSeq (protein)

NP_055317

NP_001240772
NP_001240773
NP_598890

Location (UCSC)Chr 11: 60.89 – 60.91 MbChr 19: 10.87 – 10.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM][6]

Interactions

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PRPF19 has been shown to interact with CDC5L.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000110107Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024735Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Mahajan KN, Mitchell BS (September 2003). "Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase". Proc Natl Acad Sci U S A. 100 (19): 10746–51. Bibcode:2003PNAS..10010746M. doi:10.1073/pnas.1631060100. PMC 196874. PMID 12960389.
  6. ^ a b "Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)".
  7. ^ Ajuh P, Kuster B, Panov K, Zomerdijk J C, Mann M, Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529.

Further reading

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