PWP1

Periodic tryptophan protein 1 homolog is a protein that in humans is encoded by the PWP1 gene.

PWP1
Identifiers
Aliases	PWP1, IEF-SSP-9502, PWP1 homolog, endonuclein
External IDs	MGI: 1914735; HomoloGene: 5129; GeneCards: PWP1; OMA:PWP1 - orthologs
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 C1 Start 85,665,358 bp End 85,724,960 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte nipple pylorus cardia renal medulla pericardium Achilles tendon vulva pons parietal pleura Top expressed in primitive streak abdominal wall endothelial cell of lymphatic vessel Paneth cell spermatocyte epiblast medial ganglionic eminence morula hair follicle maxillary prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function H4K20me3 modified histone binding Cellular component nucleus Golgi apparatus nucleolus chromosome Biological process transcription, DNA-templated positive regulation of stem cell differentiation histone H4-K20 trimethylation negative regulation of peptidyl-serine phosphorylation of STAT protein positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ribosome biogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11137 103136 Ensembl n/a ENSMUSG00000001785 UniProt Q13610 Q99LL5 RefSeq (mRNA) NM_007062 NM_001317962 NM_001317963 NM_133993 RefSeq (protein) NP_001304891 NP_001304892 NP_008993 NP_598754 Location (UCSC) n/a Chr 10: 85.67 – 85.72 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Gress TM, Müller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
• Honoré B, Baandrup U, Nielsen S, Vorum H (2002). "Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas". Oncogene. 21 (7): 1123–9. doi:10.1038/sj.onc.1205186. PMID 11850830. S2CID 1657629.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.