Penostatin A is a cytotoxic metabolite produced by Penicillium.[1]

Penostatin A
Names
Preferred IUPAC name
(3S,4aR,8R,9aS,9bS)-8-Hydroxy-2-methyl-3-[(1E)-non-1-en-1-yl]-4a,7,8,9,9a,9b-hexahydroindeno[5,4-b]pyran-5(3H)-one
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C22H32O3/c1-3-4-5-6-7-8-9-10-21-15(2)11-19-18-14-17(23)12-16(18)13-20(24)22(19)25-21/h9-11,13,17-19,21-23H,3-8,12,14H2,1-2H3/b10-9+/t17-,18+,19-,21-,22+/m0/s1
    Key: ONCGMAFAIBLDNP-GYGBFYAFSA-N
  • InChI=1/C22H32O3/c1-3-4-5-6-7-8-9-10-21-15(2)11-19-18-14-17(23)12-16(18)13-20(24)22(19)25-21/h9-11,13,17-19,21-23H,3-8,12,14H2,1-2H3/b10-9+/t17-,18+,19-,21-,22+/m0/s1
    Key: ONCGMAFAIBLDNP-GYGBFYAFBS
  • O=C2/C=C1/C[C@H](O)C[C@H]1[C@@H]3/C=C(/C)[C@@H](O[C@@H]23)/C=C/CCCCCCC
Properties
C22H32O3
Molar mass 344.495 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ Takahashi, Chika; Numata, Atsushi; Yamada, Takeshi; Minoura, Katsuhiko; Enomoto, Shoichi; Konishi, Katsuhiro; Nakai, Misa; Matsuda, Chitose; Nomoto, Kyosuke (1996). "Penostatins, novel cytotoxic metabolites from a Penicillium species separated from a green alga". Tetrahedron Letters. 37 (5): 655. doi:10.1016/0040-4039(95)02225-2.