Perama may refer to:
- Perama, a city near Athens, Greece
- Perama, Ioannina, a municipal unit in the Ioannina regional unit, Greece
- Perama, Rethymno, a village in the Rethymno regional unit, Greece, part of Geropotamos
- Perama (plant), a plant genus from the madder family (Rubiaceae)