Peroxins (or peroxisomal/peroxisome biogenesis factors) represent several protein families found in peroxisomes.[1] Deficiencies are associated with several peroxisomal disorders. Peroxins serve several functions including the recognition of cytoplasmic proteins that contain peroxisomal targeting signals (PTS) that tag them for transport by peroxisomal proteins to the peroxisome. Peroxins are structurally diverse and have been classified to different protein families. Some of them were predicted to be single-pass transmembrane proteins, for example Peroxisomal biogenesis factor 11.
| Peroxin | |
|---|---|
| Identifiers | |
| Symbol | PEX-2,10,12 |
| Membranome | 190 |
| Peroxin 11 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | PEX-11 | ||||||||
| Pfam | PF05648 | ||||||||
| InterPro | IPR008733 | ||||||||
| Membranome | 191 | ||||||||
| |||||||||
| Peroxin 13 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | PEX-13 | ||||||||
| Pfam | PF04088 | ||||||||
| InterPro | IPR007223 | ||||||||
| Membranome | 192 | ||||||||
| |||||||||
| Peroxin 14 | |
|---|---|
| Identifiers | |
| Symbol | PEX-14 |
| InterPro | IPR025655 |
| Membranome | 468 |
Genes
editReferences
edit- ^ Crookes WJ, Olsen LJ (February 1999). "Peroxin puzzles and folded freight: peroxisomal protein import in review". Die Naturwissenschaften. 86 (2): 51–61. Bibcode:1999NW.....86...51C. doi:10.1007/s001140050572. hdl:2027.42/41882. PMID 10084148. S2CID 22119827.
.svg){kind=small} | This biochemistry article is a stub. You can help Wikipedia by expanding it. |