Phenamidine is an antiprotozoal drug of the amidine class used in veterinary medicine. It is used to treat Babesia infection (babesiosis) dogs, horses, and cattle.[1][2] Because the drug causes frequent allergic reactions, it is usually combined with an antihistamine.[3]

Phenamidine
Clinical data
Trade namesOxopirvedine
Other names4,4'-Diamidinodiphenyl ether; 4,4'-Oxydibenzamidine
ATCvet code
Identifiers
  • 4,4’-Oxydibenzenecarboximidamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.002.692 Edit this at Wikidata
Chemical and physical data
FormulaC14H14N4O
Molar mass254.293 g·mol−1
3D model (JSmol)
Melting point215 to 216 °C (419 to 421 °F) [1]
  • O(c1ccc(C(=[N@H])N)cc1)c2ccc(cc2)C(=[N@H])N
  • InChI=1S/C14H14N4O/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)
  • Key:DMABBVCVVXMJDH-UHFFFAOYSA-N

References

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  1. ^ a b Merck Index, 11th Edition, 7165
  2. ^ Randall JB, Laws SG (May 1947). "Phenamidine in the treatment of Babesia bigemina infections of cattle". Annals of Tropical Medicine and Parasitology. 41 (1): 39–42. doi:10.1080/00034983.1947.11685310. PMID 20249289.
  3. ^ Benchchem