Phi Alpha may refer to:
- Phi Alpha Literary Society, a men's literary society founded in 1845 at Illinois College
- Phi Alpha (fraternity), a historically Jewish fraternity founded at George Washington University on October 14, 1914, which merged into Phi Sigma Delta in April 1959 (which in turn merged into Zeta Beta Tau)
- Phi Alpha (honor society), an honor society in the field of social work founded in 1962
- Phi Alpha, the motto of social fraternity Sigma Alpha Epsilon