Phospholipase B, also known as lysophospholipase, is an enzyme with a combination of both PLA1 and PLA2 activities; that is, it can cleave acyl chains from both the sn-1 and sn-2 positions of a phospholipid. In general, it acts on lysolecithin (which is formed by the action of PLA2 on lecithin).

phospholipase B1
Identifiers
SymbolPLB1
NCBI gene151056
HGNC30041
OMIM610179
RefSeqNM_153021
UniProtQ6P1J6
Other data
LocusChr. 2 p23.3
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StructuresSwiss-model
DomainsInterPro
Phospholipase cleavage sites. An enzyme that displays both PLA1 and PLA2 activities is called a phospholipase B.

See also

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References

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  • Vance JE, Vance DE (14 March 2008). Biochemistry of Lipids, Lipoproteins and Membranes. Elsevier. pp. 312–313. ISBN 978-0-08-055988-9.