Phosphomannan mannosephosphotransferase

In enzymology, a phosphomannan mannosephosphotransferase (EC 2.7.8.9) is an enzyme that catalyzes the chemical reaction

phosphomannan mannosephosphotransferase
Identifiers
EC no.2.7.8.9
CAS no.37278-31-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
GDP-mannose + (phosphomannan)n GMP + (phosphomannan)n+1

Thus, the two substrates of this enzyme are GDP-mannose and (phosphomannan)n, whereas its two products are GMP and (phosphomannan)n+1.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is GDP-mannose:phosphomannan mannose phosphotransferase.

References

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  • Bretthauer RK, Kozak LP, Irwin WE (1969). "Phosphate and mannose transfer from guanosine diphosphate mannose to yeast mannan acceptors". Biochem. Biophys. Res. Commun. 37 (5): 820–827. doi:10.1016/0006-291X(69)90965-6. PMID 4311996.