Pilsener may refer to:
- anything from the city of Plzeň (German: Pilsen)
- Pilsner, a type of beer
- Beer glassware#Pilsner glass, a variety of beer glass
- Mash ingredients#Pilsner malt, a type of brewing malt
- Prohibition in Iceland#Pre-abolition, non-alcoholic beer in Iceland during prohibition, usually mixed in such drinks as bjórlíki, a legal beer substitute
- Old Style Pilsner, a beer brewed in Canada by Molson's popularly known simply as Pilsner in regions where it is widely consumed