Piperidinones or piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine.[1] This multicomponent reaction is related to the Hantzsch pyridine synthesis.
Piperidinones
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edit- ^ Petrenko-Kritschenko P, Zoneff N (March 1906). "Ueber die Condensation von Aceton‐dicarbonsäureestern mit Benzaldehyd unter Anwendung von Ammoniak". Berichte der Deutschen Chemischen Gesellschaft (in German). 39 (2): 1358–61. doi:10.1002/cber.19060390234.
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