Pisarek is a surname. Notable people with the surname include:
- Avraham Pisarek (1901–1983), German photographer
- Kasia Pisarek (born Katarzyna Krzyżagórska), Polish art expert
- Maciej Pisarek (born 1966), Polish film director and screenplay writer
- Marian Pisarek (1912–1942), Polish fighter pilot and flying ace of World War II