RUF1 is a non-coding RNA (ncRNA) present within the plasmodium genome. Bioinformatic studies predicted that RUF1 was present in the plasmodium genome and the expression of this ncRNA was verified by northern blot.[1] The location of this ncRNAs was subsequently mapped within the P. falciparum strain 3DF genome by primer extension. RUF1 is a novel RNA of unknown function but has shown to contain some structural similarity with the H/ACA box snoRNA but no known targets have been identified.

Plasmodium RNA of unknown function 1
Identifiers
SymbolRUF1
RfamRF01578
Other data
RNA typesRNA
Domain(s)Plasmodium
PDB structuresPDBe

References

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  1. ^ Chakrabarti K, Pearson M, Grate L, Sterne-Weiler T, Deans J, Donohue JP, Ares M (November 2007). "Structural RNAs of known and unknown function identified in malaria parasites by comparative genomics and RNA analysis" (Free full text). RNA. 13 (11): 1923–1939. doi:10.1261/rna.751807. PMC 2040097. PMID 17901154. Archived from the original on 2023-02-10. Retrieved 2015-08-28.
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