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The Poribacteria-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] The Poribacteria-1 motif is found only in the candidate bacterial phylum known as Poribacteria, and all 6 Poribacteria-1 RNAs are actually found in one organism, Candidatus Poribacteria sp. WGA-4E. All but one of these RNAs occur within roughly 6 kilobases of genomic DNA, and each of the 5 RNAs occurs between a different pair of protein-coding genes. This arrangement could suggest that the motif functions on the level of single-stranded DNA as attC sites that are part of an integron. It is also possible that Poribacteria-1 RNAs are cis-regulatory elements that regulate genes that happen to often be nearby to one another, or that the RNAs function in trans as small RNAs.
| Poribacteria-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of Poribacteria-1 RNA | |
| Identifiers | |
| Symbol | Poribacteria-1 |
| Rfam | RF03113 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.