The episodes of the Yozakura Quartet anime are based on the manga series of the same name by Suzuhito Yasuda. They are directed by Kou Matsuo and produced by the animation studio Nomad. The plot of the episodes follows the members of the Hiizumi Life Counseling Office, Akina Hiizumi, a human that can use "tuning" to return yōkai to their world; Hime Yarizakura, a dragon yōkai who is the mayor of the town of Sakurashin; Ao Nanami, a satori with telepathic abilities; and Kotoha Isone, a half-human, half-yōkai who can conjure objects with her words. Together, they protect the townspeople of Sakurashin, a city where humans and yōkai coexist with one another.
The episodes aired from October 2, 2008 to December 18, 2008 on Tokyo Broadcasting System in Japan. Other networks that broadcast the episodes include BS-i, Chubu-Nippon Broadcasting, and Mainichi Broadcasting System. The anime adaptation of the manga was first confirmed in Kodansha's Monthly Shōnen Sirius magazine on March 26, 2008. (Full list...)