- April 16, 2000 — Ukraine's national referendum takes place on the issue of reformation the governing system of Ukraine.
- April 22, 2006 — Two homemade bombs exploded in different supermarkets in the Ukrainian city of Kharkiv.
- April 26, 1986 — Reactor No. 4 of the Chernobyl Nuclear Power Plant exploded at 01:23 A.M.
- April 29, 1918 — Constitution of the Ukrainian People's Republic, a constitutional document, was approved by the Central Rada, but never announced.
- April 29, 1918 — The Holiday of Ukrainian Sea. On this day the main parts of Black Sea fleet in Sevastopol hoisted ukrainian flags.