Portillo may refer to:
- Portillo (surname), including a list of people with the surname
- Portillo de Toledo, Spain
- Portillo, Valladolid, Spain
- Portillo, Chile
- Portillo's Restaurants
- Portillo, Adjuntas, Puerto Rico, a barrio of Adjuntas, Puerto Rico
This disambiguation page lists articles associated with the title Portillo.
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If an internal link led you here, you may wish to change the link to point directly to the intended article.