In organic chemistry, the principle of least motion is the hypothesis that when multiple species with different nuclear structures could theoretically form as products of a given chemical reaction, the more likely to form tends to be the one requiring the least amount of change in nuclear structure or the smallest change in nuclear positions.[1]
References
edit- ^ Hine J (1977). "The principle of least nuclear motion". Advances in Physical Organic Chemistry. 15: 1–61. doi:10.1016/S0065-3160(08)60117-3.
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