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2002–2004 SARS outbreak

(Redirected from Progress of the SARS outbreak)

The 2002–2004 outbreak of SARS, caused by severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), infected over 8,000 people from 30 countries and territories, and resulted in at least 774 deaths worldwide.[1]

2002–2004 SARS outbreak
A map of the infected countries of the epidemic of SARS between 1 November 2002 and 7 August 2003
  Countries with confirmed deaths
  Countries with confirmed infections
  Countries without confirmed cases
A map of SARS cases and deaths around the world regarding the global population
DiseaseSARS
Virus strainSARS-CoV-1
LocationWorldwide (Mostly in East Asia)
First outbreakShunde, Guangdong, China
Index case16 November 2002
Arrival dateEarly 2003
Date16 November 2002 – 19 May 2004 (1 year, 6 months and 3 days)
Confirmed cases8,096
Deaths
774
Territories
Around 30 countries

The outbreak was first identified in Foshan, Guangdong, China, in November 2002.[2] The World Health Organization (WHO) was notified of the outbreak in February 2003, and issued a global alert in March 2003. Initially, the cause of the outbreak was unknown, and some media outlets reported that an influenza virus was a potential culprit.[3] The major part of the outbreak lasted about 8 months, and the World Health Organization declared SARS contained on 5 July 2003. However, several SARS cases were reported until May 2004.[4]

In late December 2019, SARS-CoV-2, a coronavirus in the same genus as the one that caused SARS, was discovered in Wuhan, Hubei, China. This strain causes COVID-19, which spread to other areas of Asia, and then worldwide in early 2020, marking the start of the COVID-19 pandemic.[5][6]

Outbreak by country and territory

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2003 probable cases of SARS worldwide
Probable cases of SARS by country and territory,
1 November 2002 – 31 July 2003[7]
Country or region Cases Deaths Fatality (%)
  China[a] 5,327 349 6.6
  Hong Kong 1,755 299 17.0
  Taiwan[b][8][9] 346 73 21.1
  Canada 251 43 17.1
  Singapore 238 33 13.9
  Vietnam[10] 63 5 7.9
  United States 27 0 0
  Philippines 14 2 14.3
  Thailand 9 2 22.2
  Germany 9 0 0
  Mongolia 9 0 0
  France 7 1 14.3
  Australia 6 0 0
  Malaysia 5 2 40.0
  Sweden 5 0 0
  United Kingdom 4 0 0
  Italy 4 0 0
  India 3 0 0
  South Korea 3 0 0
  Indonesia 2 0 0
  South Africa 1 1 100.0
  Kuwait 1 0 0
  Ireland 1 0 0
  Macau 1 0 0
  New Zealand 1 0 0
  Romania 1 0 0
  Russia 1 0 0
  Spain 1 0 0
   Switzerland 1 0 0
Total excluding China 2,769 425 15.4
Total (30 territories) 8,096 774 9.6
  1. ^ Figures for China exclude Hong Kong, Macau and Taiwan, which are reported separately by the WHO.
  2. ^ After 11 July 2003, 325 Taiwanese cases were 'discarded'. Laboratory information was insufficient or incomplete for 135 of the discarded cases; 101 of these patients died.

Timeline

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November 2002

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On 16 November 2002,[11] an outbreak of severe acute respiratory syndrome (SARS) began in China's Guangdong province, bordering Hong Kong. The first case of infection was traced to Foshan.[12][13] This first outbreak affected people in the food industry, such as farmers, market vendors, and chefs.[14][15] The outbreak spread to healthcare workers after people sought medical treatment for the disease.[15] The People's Republic of China notified the World Health Organization (WHO) about this outbreak on 11 February 2003, reporting 305 cases including 105 health-care workers and five deaths.[16] Later it reported that the outbreak in Guangdong had peaked in mid-February 2003. However, this appears to have been false because subsequently 806 cases of infection and 34 deaths were reported.[17] Italian physician Carlo Urbani was the first to identify SARS as probably a new and dangerously contagious viral disease.[18][19]

Early in the epidemic, the Chinese government discouraged its press from reporting on SARS, delayed reporting to WHO, and initially did not provide information to Chinese outside Guangdong province, where the disease is believed to have originated.[20] Also, a WHO team that travelled to Beijing was not allowed to visit Guangdong province for several weeks.[21] This resulted in international criticism, which seems to have led to a change in government policy in early April.[22][23]

January 2003

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A fishmonger, named Zhou Zuofen, checked in to the Sun Yat-sen Memorial Hospital in Guangzhou on 31 January, where he infected 30 nurses and doctors. The virus soon spread to nearby hospitals.[24]

February 2003

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Hong Kong

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Ninth floor layout of the Hotel Metropole in Hong Kong, showing where an outbreak of the severe acute respiratory syndrome (SARS) occurred

In February 2003, Liu Jianlun became Hong Kong's SARS index patient. He had come to attend a family wedding gathering; Liu was on the staff at Sun Yat-Sen Memorial Hospital in Guangzhou and had treated SARS patients.[25]

On 21 February, Liu and his wife checked into room 911 on the ninth floor of the Metropole Hotel. Despite feeling ill he visited with his family and they traveled around Hong Kong. By the morning of 22 February, he knew he was very sick and walked to the Accident and Emergency Department of Kwong Wah Hospital to seek treatment. He was treated by the triage nurse and doctor without protective measures even though a memorandum on surveillance of severe community-acquired pneumonia had been issued by the Hospital Authority of Hong Kong. After Liu's chest X-ray taken in Kwong Wah Hospital became available, staff became aware of the situation, wearing personal protective equipment and full isolation inside the ICU.[26] He had not recovered and died on 4 March.

Liu is believed to have been a SARS super-spreader: 23 other Metropole guests developed SARS, including seven from the ninth floor. Liu's brother-in-law, who sought treatment in late February, was hospitalized in Kwong Wah Hospital on 1 March and died on 19 March. It is estimated that around 80% of the Hong Kong cases were due to Liu.[27]

Vietnam

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The virus was carried to Hanoi, Vietnam, by Chinese-American Johnny Chen, a resident of Shanghai who had roomed across the hall from Liu at the Metropole. He was admitted to the French Hospital of Hanoi on 26 February, where he infected at least 38 members of the staff. Even though he was evacuated to Hong Kong, he died on 13 March.[27] Carlo Urbani, a World Health Organization (WHO) infectious disease specialist, was among the staff who examined Chen. Urbani observed that other hospital staff were already falling ill and realized that he was dealing with a new and dangerous disease. He himself became infected and died on 29 March.[27]

Canada

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Further information: 2002–2004 SARS outbreak among healthcare workers

On 23 February, an elderly woman named Kwan Sui-Chu who had also been a Metropole Hotel guest, returned to Toronto, Canada, from Hong Kong. She died at home on 5 March, after infecting her son Tse Chi Kwai, who subsequently spread the disease to Scarborough Grace Hospital and died on 13 March.[28]

March 2003

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Singapore

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On 1 March, 26-year-old Esther Mok, another Metropole guest, was admitted to Tan Tock Seng Hospital after visiting Hong Kong, starting the outbreak in Singapore. Although she recovered, various family members did not.[29]

Taiwan

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The first cases of atypical pneumonia in Taiwan were identified in a Guangdong-based businessman and his wife on 14 March and confirmed on 17 March. He had returned to Taiwan via Hong Kong on 23 February and reported a fever two days later. His wife became ill after caring for him, and both were admitted to National Taiwan University Hospital.[30] Taiwan's third case of the disease was identified in a Yilan hospital on 15 March. Like the first case, the third case appeared in someone who had traveled to Guangdong and transited through Hong Kong before arriving in Taiwan.[31] Shortly after the third case was diagnosed, officials from the Centers for Disease Control and Prevention in the United States traveled to Taiwan to study the disease.[32][33] The fourth case, in another traveler to Guangdong, was identified in Chiayi on 18 March, after he sought treatment at a hospital the previous day.[34] By 22 March, six cases in Taiwan had matched the World Health Organization definition of probable.[35]

Hong Kong

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See also: Amoy_Gardens § SARS_outbreak

On 4 March, a 27-year-old man, who had visited a guest on the Metropole's 9th floor 11 days earlier, was admitted to Hong Kong's Prince of Wales Hospital. At least 99 hospital workers (including 17 medical students) were infected while treating him.[36]

On 11 March, Carlo Urbani travelled to Bangkok, Thailand, to attend a medical conference. He fell ill during the flight and told a friend waiting at Bangkok not to touch him, to call an ambulance and take him to a hospital. He was isolated in an intensive care unit. A similar outbreak of a mysterious respiratory infection was reported among Hong Kong healthcare workers.[37][38]

On 12 March, WHO issued a global alert about a new infectious disease of unknown origin in both Vietnam and Hong Kong. On 15 March, WHO issued a heightened global health alert about a mysterious pneumonia with a case definition of SARS after cases in Singapore and Canada were also identified. The alert included a rare emergency travel advisory to international travelers, healthcare professionals, and health authorities. The Centers for Disease Control (CDC) issued a travel advisory stating that persons considering travel to the affected areas in Asia (Hong Kong, Singapore, Vietnam, and China) should not go.[39][40][41]

On 17 March, an international network of 11 laboratories was established to determine the cause of SARS and develop potential treatments.[42]

On 25 March, Hong Kong authorities stated that nine tourists had contracted the disease from a mainland Chinese man who had boarded the same plane on 15 March, Air China Flight 112 to Beijing.[43]

On 27 March, Arthur K. C. Li, head of the Hong Kong Education and Manpower Bureau, announced cancellation of all classes in educational institutions. The Ministry of Education in Singapore announced that all primary schools, secondary schools, and junior colleges were to be shut until 6 April 2003. Polytechnics and universities were not affected.[44] On 29 March, Urbani died in Bangkok.[38]

On 30 March, Hong Kong authorities quarantined estate E of the Amoy Gardens housing estate due to a massive (200+ cases) outbreak in the building. The balcony was completely closed and guarded by the police. The residents of the building were later transferred to the quarantined Lei Yue Mun Holiday Camp and Lady MacLehose Holiday Village on 1 April because the building was deemed a health hazard.[citation needed]

Most of the cases were linked to apartments with a north-western orientation which shared the same sewage pipe. According to government officials, the virus was brought into the estate by an infected kidney patient (the type of kidney illness was not specified) after discharge from Prince of Wales Hospital, who visited his elder brother living on the seventh floor. Through excretion, the virus spread through drainage. One theory speculated that the virus was spread by airborne transmission, through dried up U-shaped P-traps in the drainage system which a maritime breeze blew into the estate's balconies and stairwell ventilation. It was confirmed that the virus spread via droplets, but this later outbreak made officials question the possibility that the virus could be spread through the air.[45]

April 2003

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On 1 April, the U.S. government called back non-essential personnel in their consulate office in Hong Kong and Guangzhou. The US government also advised US citizens not to travel to the region.[citation needed]

On 2 April, Chinese medical officials began reporting the status of the SARS outbreak. China's southern Guangdong province reported 361 new infections and 9 new deaths, increasing the total Mainland China figures previously reported at end-February. The virus was also detected in Beijing and Shanghai. The WHO also advised travellers to avoid Hong Kong and Guangdong during a press briefing.[46]

On 3 April, a WHO team of international scientists landed in Guangzhou from Beijing to discuss with officials, but the team was yet to inspect any suspected origin or any medical facilities on the progress of infection control. Fifteen of the quarantined Amoy Gardens residents at Lei Yue Mun Holiday Camp were relocated to the Sai Kung Outdoor Recreation Centre after an overnight protest on washroom sharing. The first medical worker infected with SARS died in Hong Kong. The doctor's daughter and infected wife survived his illness, although the wife was also among the quarantined medical workers under intensive care. Hong Kong school closures were extended by two weeks to 21 April.[citation needed]

On 4 April, the WHO team inspected the first infection case in Foshan County. The person infected four people but did not infect his family. A 40-year-old woman became the first local case in Shanghai. A Chinese health specialist admitted at a press conference to not informing the public early enough about the outbreak. The PRC Health Minister also claimed that the disease has been under control in most parts of mainland China. He also released the names of seven drugs which he claimed to be effective in curing SARS. WHO officials said that the information provided by the PRC about the disease has been "very detailed".[citation needed] US government enforced compulsory quarantine of an infected person.[citation needed]

On 5 April, the Singapore government announced that school closures would be extended. Junior colleges were to reopen on 9 April, secondary schools would reopen on 14 April and primary schools and pre-schools would reopen on 16 April.[47] On 6 April, a SARS case was found in Manila, a person who had returned from Hong Kong.[citation needed]

On 8 April, SARS was discovered in the Lower Ngau Tau Kok Estate near Amoy Gardens in Kowloon. Hong Kong health officials warned that SARS had spread so far domestically and abroad that it was here to stay. Nevertheless, WHO officials remained cautiously optimistic that the disease could still be contained.[48]

On 9 April, James Earl Salisbury died of SARS at a hospital in Hong Kong. An American Mormon[49] and a teacher at Shenzhen Polytechnic,[50] he had been sick for approximately one month before his death, but he was originally diagnosed with pneumonia.[51] His son Michael "Mickey" Salisbury was with him in China and also contracted the disease, but he survived it.[52] Salisbury's death led to more open admissions by the Chinese government about the spread of SARS.[53]

On 10 April, Jim Hughes, the head of infectious disease at the CDC, confirming the warnings of Hong Kong health officials, claimed that he believed that SARS could no longer be eradicated in the Far East. However, he remained hopeful that it could be prevented from spreading widely in North America.[54] On 11 April, the World Health Organization issued a global health alert for SARS as it became clear the disease was being spread by global air travel.[citation needed]

On 12 April, Marco Marra, director of the Michael Smith Genome Sciences Centre, which is part of the British Columbia Cancer Agency, announced that scientists at his centre had broken the genetic code of the virus suspected of causing the disease.[55] In Toronto, three more people died of SARS, bringing the Canadian death toll to 13. On 16 April, the WHO issued a press release stating that the coronavirus identified by a number of laboratories was the official cause of SARS. The virus was officially named the SARS virus.[56]

On 17 April, the first confirmed case of SARS from India was reported.[57][58] On 19 April, Premier of the People's Republic of China Wen Jiabao announced that there would be severe consequences for local officials who did not report SARS cases in a timely and accurate manner, signaling a major change in policy. SARS had also been gaining prominence in the mainland Chinese media; by late April, it had jumped from virtual invisibility onto the front page, with daily reports from all provinces on new cases and measures.[citation needed]

On 20 April, Beijing's mayor Meng Xuenong and the health minister of the PRC Zhang Wenkang were replaced respectively by Wang Qishan from Hainan and the former deputy health minister Gao Qiang. They were the first two high-rank officials in the PRC to be dismissed because of the fallout of the epidemic. In the news conference chaired by Gao Qiang several hours earlier, the PRC admitted that in Beijing there were more than 300 cases, as opposed to the previous figure of only 37. The figure had increased to 407 the following day. Chinese officials also admitted to major underreporting of cases, which were attributed to bureaucratic ineptitude.[citation needed]

On 22 April, schools in Hong Kong started to reopen in stages. On 23 April, Beijing announced that all primary and secondary schools would be closed for two weeks.[59] A few days before, some colleges in Peking University had been closed because some students had been infected. The WHO issued travel advisories against Beijing, Toronto, and Shanxi.[60]

After several cases of SARS were diagnosed in Taiwan throughout the month of April,[61] including a cluster at Taipei Municipal Hospital's Hoping branch,[62][63] the Taipei City Government closed that hospital and quarantined its 930 staff and 240 patients for two weeks.[64] The decision to lock down the medical facility was protested by hospital staff.[65]

On 24 April, the Hong Kong Government announced an HK$11.8 billion relief package designed to assist Hong Kong's battered tourism, entertainment, retail, and catering sectors, consisting of a waiver of tourism- and transport-related license fees, and HK$1 billion allocated for tourism promotion overseas. The package also includes a salaries tax rebate and reduced rates.[citation needed]

On 26 April, Wu Yi was named Zhang Wenkang's replacement as PRC health minister. On 26–27 April, Chinese authorities locked down Beijing, closing down theatres, discos, and other entertainment venues in Beijing as the death toll in Beijing continued to rise, threatening to become the worst-hit area of the country, eclipsing the province of Guangdong. People who may have been exposed were ordered to stay home. Authorities were bolstered by the fact that the infection rate seemed to have declined, with Guangdong only exporting three new infections over the weekend. The economic impact was becoming dramatic as shops, restaurants, markets, bars, universities, schools, and many other businesses had closed, while some government ministries and large state banks were working with minimal staff levels.[citation needed]

On 28 April, WHO declared the outbreak in Vietnam to be over as no new cases were reported for 20 days. On 29 April, leaders of member countries of ASEAN and the PRC premier held an emergency summit in Bangkok, Thailand to address the outbreak. Among the decisions made were the setting-up of a ministerial-level task force and uniform pre-departure health screening in airports.[citation needed]

On 30 April, the World Health Organization lifted the SARS travel warning for Toronto. The decision was made because "it is satisfied with local measures to stop the spread of SARS". Canadian officials said they would step up screenings at airports.[66]

May 2003

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On 3 May, the 2003 FIFA Women's World Cup was abruptly moved to the United States due to the outbreak. China maintained its automatic qualification and later hosted the Women's World Cup four years later. On 4 May, the newly infected number of people in Hong Kong dropped to single digits. On 19 May, the WHO Annual Meeting was held in Geneva. Hong Kong pushed for the Tourism Warning to be lifted.[citation needed]

On 20 May, the WHO refused to lift the Tourism Warning for Hong Kong and Guangdong, but did so three days later after a recount of the number of SARS patients. On 24 May, the number of newly infected patients reached zero for in Hong Kong, the first time since the outbreak in the territory in March.[citation needed]

On 24 May, a new cluster of about 20 suspected patients was reported in Toronto. By 29 May, more than 7,000 people were instructed to quarantine themselves in Canada by authorities seeking to control the potential spread of the SARS outbreak.[67]

In Taiwan, administrators and staff of Taipei Municipal Hospital's Hoping branch faced disciplinary action from the Taipei City Government.[68][69][70][71] The Control Yuan also launched an investigation into the hospital's closure.[72] Taipei City Bureau of Health director Chiu Shu-ti resigned from Ma Ying-jeou's mayoral administration on 25 May.[73][74] On 27 May, the Taichung City Government, led by mayor Jason Hu, established a command center in central Taiwan to handle SARS.[75] The Department of Health worked with several hospitals in Taiwan to expand medical facilities and treatment for SARS patients.[76]

On 31 May, Singapore was removed from WHO's list of 'Infected Areas'.[citation needed]

June 2003

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On 10 June, the government of Ontario created the SARS Commission inquiry in order to "investigate the recent introduction and spread of SARS" in the province.[77]

On 23 June, Hong Kong was removed from WHO's list of 'Affected Areas', while Toronto, Beijing, and Taiwan remained. On 27 June, the World Health Organization stated that the world population should be SARS-free within the next two to three weeks, but warned the disease could emerge in China next winter.[78]

July 2003

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On 2 July, Canada was removed from the WHO's list of 'Infected Areas'.[citation needed]

On 5 July, WHO declared the SARS outbreak contained and removed Taiwan from the list of affected areas.[79][78] Taiwan's removal from the list signified the end of the outbreak.[80]

September 2003

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On 8 September, Singapore announced that a post-doctoral worker in a SARS research lab in the National University of Singapore had contracted the disease while working on the West Nile virus but recovered shortly thereafter. It was suspected that the two viruses mixed while he was doing his research.[citation needed]

December 2003

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On 10 December, a researcher in a SARS lab in Taiwan was found infected with SARS after returning from Singapore attending a medical conference;[81] 74 people in Singapore were quarantined but none of them were infected.

On 27 December, China announced the first suspected case of SARS in six months in Guangdong in an individual who was not a SARS researcher.[citation needed]

January 2004

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On 5 January, China confirmed that the case reported in December was a case of wild source SARS. The Philippines announced a possible case in a person just returned from Hong Kong. The patient was later determined to have had pneumonia and not SARS. In China, Asian palm civets were culled in markets (the civets were thought to be a reservoir for the disease).[citation needed]

On 10 January, a restaurant worker in Guangdong was confirmed as the second wild source SARS since the outbreak was contained. Guangzhou was also the site of the first case in December and was thought to be the origin of the virus in the original outbreak. Three Hong Kong television reporters who visited SARS-related sites in Guangzhou were declared free of the disease. On 17 January, China announced a third case of SARS in Guangzhou. WHO officials urged more testing to bring the three recently announced cases into line with their standards; however, they also announced SARS virus had been detected by a WHO team in civet cages at the restaurant where the second case worked and in civet cages in the market.[citation needed]

On 31 January, China announced the fourth case of SARS as a 40-year-old doctor from the southern city of Guangzhou, and gave his family name as Liu. He was discharged when the announcement was made.[citation needed]

April 2004

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SARS broke out again in Beijing and in Anhui Province. On 22 April, China announced that a 53-year-old woman had died on 19 April, its first SARS death since June. One person died and nine were infected in the outbreak which was first reported on 22 April.[82] The first 2 infected cases involved a postgraduate student and a researcher at the National Institute for Viral Disease Control and Prevention (abbrev.: Institute of Virology) of the Chinese Center for Disease Control and Prevention; an additional 7 cases were diagnosed, which were linked with close personal contact with the student, the lab or with a nurse who treated the student.[83]

May 2004

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Two additional confirmed cases of SARS and three additional suspected cases were reported in Beijing on 1 May, all related to a single research lab, the Diarrhea Virus Laboratory in the CDC's National Institute of Virology in Beijing.[84] "The cases had been linked to experiments using live and inactive SARS coronavirus in the CDC's virology and diarrhea institutes where interdisciplinary research on the SARS virus was conducted."[82] The total number of cases was six, with four in Beijing and two in Anhui.[citation needed]

On 2 May, China announced the three suspected cases as genuine cases of SARS, bringing the total cases in a recent outbreak to nine. 189 people were released from quarantine. On 18 May, after no new infections had been reported in a three-week period, WHO announced China as free of further cases of SARS, but stated that "biosafety concerns remain".[4]

Subsequent status

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In May 2005, Jim Yardley of the New York Times wrote:

"Not a single case of the severe acute respiratory syndrome has been reported this year [2005] or in late 2004. It is the first winter without a case since the initial outbreak in late 2002. In addition, the epidemic strain of SARS that caused at least 774 deaths worldwide by June 2003 has not been seen outside of a laboratory since then."[85]

Policy impact

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In China, the SARS epidemic resulted in substantial public criticism, prompted government statements that privatizing health care in rural China had been a failure, and brought rural reform to the top of the policy agenda.[86]: 104–105 

Following the outbreak, China strengthened its reporting mechanisms for contagious diseases and reduced the reporting time from grassroots healthcare worked to the China Center for Disease Control and Prevention from 15 days to 4 hours.[87]: 67 

See also

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References

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Citations

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  1. ^ "How SARS terrified the world in 2003, infecting more than 8,000 people and killing 774". Business Insider. 20 February 2020. Archived from the original on 2 March 2020. Retrieved 2 March 2020.
  2. ^ "A Chronicle on the SARS Epidemic". Chinese Law & Government. 36 (4): 12–15. July–August 2003. doi:10.2753/CLG0009-4609360412. ISSN 0009-4609. S2CID 219305114. Archived from the original on 2 October 2020. Retrieved 12 June 2020.
  3. ^ "Alert over Hong Kong 'super-flu'". 13 March 2003. Archived from the original on 25 October 2021. Retrieved 25 October 2021 – via news.bbc.co.uk.
  4. ^ a b WHO (18 May 2004). "China's latest SARS outbreak has been contained, but biosafety concerns remain – Update 7". World Health Organization. Archived from the original on 12 February 2020. Retrieved 14 February 2020.
  5. ^ "New coronavirus stable for hours on surfaces". National Institutes of Health (NIH). NIH.gov. 17 March 2020. Archived from the original on 23 March 2020. Retrieved 4 May 2020.
  6. ^ "Coronavirus Disease (COVID-19) Situation Reports: Data as reported by: 20 January 2020" (PDF). www.who.int. WHO. Archived (PDF) from the original on 29 January 2020. Retrieved 3 September 2020.
  7. ^ "Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003". World Health Organization. 21 April 2004. Archived from the original on 19 March 2020. Retrieved 3 March 2020.
  8. ^ "衛生署針對報載SARS死亡人數有極大差異乙事提出說明" [DH's statement on significant differences in reported SARS deaths] (in Simplified Chinese). 台灣衛生福利部疾病管制署 (Disease Control Agency, Taiwan Ministry of Health and Welfare). Archived from the original on 20 March 2020. Retrieved 3 March 2020.
  9. ^ "十年前SARS流行 346人感染73死亡" [Ten years ago SARS epidemic 346 people infected 73 died] (in Simplified Chinese). Public Television Service. 25 April 2013. Archived from the original on 19 February 2020. Retrieved 3 March 2020.
  10. ^ "Hồi ức 45 ngày kinh hoàng chống dịch SARS". benhnhietdoi.vn (in Vietnamese). Archived from the original on 3 April 2023. Retrieved 3 April 2023.
  11. ^ Dan, Feng; De Vlas, Sake J.; Fang, Li-Qun; Han, Xiao-Na; Zhao, Wen-Juan; Shen, Sheng; Yang, Hong; Jia, Zhong-Wei; Richardus, Jan Hendrik; Cao, Wu-Chun (27 October 2009). "The SARS epidemic in mainland China: bringing together all epidemiological data". Tropical Medicine and International Health. 14 (s1): 4–13. doi:10.1111/j.1365-3156.2008.02145.x. PMC 7169858. PMID 19508441.
  12. ^ Xu, Rui-Heng; He, Jian-Feng; Evans, Meirion R.; Peng, Guo-Wen; Field, Hume E.; Yu, De-Wen; Lee, Chin-Kei; Luo, Hui-Min; Lin, Wei-Sheng; Lin, Peng; Li, Ling-Hui; Liang, Wen-Jia; Lin, Jin-Yan; Schnur, Alan (June 2004). "Epidemiologic Clues to SARS Origin in China". Emerging Infectious Diseases. 10 (6): 1030–1037. doi:10.3201/eid1006.030852. PMC 3323155. PMID 15207054.
  13. ^ Horstman, Mark (7 April 2003). "The facts about SARS". Australian Broadcasting Corporation. Archived from the original on 24 December 2019. Retrieved 25 May 2020.
  14. ^ Martin, Nik (22 January 2020). "SARS remembered – how a deadly respiratory virus hit Asian economies". Deutsche Welle. Archived from the original on 12 June 2020. Retrieved 25 May 2020.
  15. ^ a b Rosenthal, Elisabeth (27 April 2003). "The SARS Epidemic: The Path; From China's Provinces, a Crafty Germ Breaks Out". The New York Times. Archived from the original on 22 May 2020. Retrieved 25 May 2020.
  16. ^ Severe Acute Respiratory Syndrome (SARS) – multi-country outbreak – Update 6. Archived 3 May 2009 at the Wayback Machine World Health Organization (www.who.int). Retrieved 22 January 2020
  17. ^ Cyranoski, D. (2003). "China joins investigation of mystery pneumonia". Nature. 422 (6931): 459. Bibcode:2003Natur.422..459C. doi:10.1038/422459b. PMC 7094955. PMID 12673214.
  18. ^ Coates, Sam; Asthana, Anushka. "Dr Carlo Urbani Health expert who identified the Sars outbreak as an epidemic, and was killed by the virus". The Times. London. Archived from the original on 5 June 2011. Retrieved 14 December 2020.(subscription required)
  19. ^ "Dr. Carlo Urbani of the World Health Organization dies of SARS". WHO. 29 March 2003. Archived from the original on 5 June 2003. Retrieved 23 January 2020.
  20. ^ Rosenthal, E.; Altman, L. K. (27 March 2003). "China Raises Tally of Cases and Deaths in Mystery Illness". The New York Times. Archived from the original on 6 May 2009. Retrieved 11 March 2009.
  21. ^ "IDEESE Case: SARS". Archived from the original on 27 April 2015. Retrieved 20 April 2015.
  22. ^ "The SARS Epidemic". International Dimensions of Ethics Education in Science and Engineering Project. University of Massachusetts Amherst. Archived from the original on 12 June 2020. Retrieved 20 May 2020.
  23. ^ Ching, Frank (2 May 2003). "Sars Gives China a Lesson in Globalization". YaleGlobal. Yale University. Archived from the original on 12 June 2020. Retrieved 20 May 2020.
  24. ^ Peter McGrath (12 February 2013). "Scientists wait for next mass killer to spill over from nature" (Zhou is erroneously named Zhou Zoufeng in the article). The Yorkshire Post. Archived from the original on 26 January 2020. Retrieved 26 January 2020.
  25. ^ Abraham, Thomas (2004). Twenty-first Century Plague: The Story of SARS. Johns Hopkins University Press. ISBN 9780801881244. Archived from the original on 26 February 2020. Retrieved 22 January 2020 – via archive.org.
  26. ^ "Select Committee to inquire into the handling of the Severe Acute Respiratory Syndrome outbreak by the Government and the Hospital Authority". www.legco.gov.hk. Archived from the original on 19 April 2021. Retrieved 13 October 2021.
  27. ^ a b c Khan, Ali S. & Patrick, William. (2016). "The Next Pandemic." New York: PublicAffairs.
  28. ^ Low, Donald (2004). Learning from SARS: Preparing for the Next Disease Outbreak: Workshop Summary. National Academies Press (US). pp. 63–71. Archived from the original on 24 February 2020. Retrieved 28 February 2020.
  29. ^ Yeoh, En-Lai (9 April 2003). "Singapore Woman Linked to 100 SARS Cases". Associated Press. Archived from the original on 18 June 2013. Retrieved 28 February 2020.
  30. ^ "Mystery bug strikes Taiwan couple". Taipei Times. Central News Agency. 15 March 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  31. ^ Chen, Melody (16 March 2003). "A third case of atypical pneumonia reported in Taiwan". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  32. ^ Chen, Melody (17 March 2020). "US specialists to study pneumonia cases". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  33. ^ Chen, Melody (18 March 2003). "Mystery illness highlights Taiwan's health isolation". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  34. ^ Chen, Melody; Ko, Shu-ling; Lin, Mei-chun (19 March 2003). "Fourth mystery pneumonia case confirmed in Chiayi". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  35. ^ "WHO pinpoints six 'probable' SARS cases in Taiwan". Taipei Times. 23 March 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  36. ^ "Update: Outbreak of Severe Acute Respiratory Syndrome – Worldwide, 2003". Archived from the original on 27 April 2015. Retrieved 20 April 2015.
  37. ^ "WHO Director-General's remarks at the Opening Ceremony of the Carlo Urbani Museum – 1 April 2023". www.who.int. Retrieved 26 June 2024.
  38. ^ a b Fleck, F. (12 April 2003). "Carlo Urbani". BMJ. 326 (7393): 825. doi:10.1136/bmj.326.7393.825. ISSN 0959-8138.
  39. ^ Mackenzie, J.S.; Drury, P.; Ellis, A.; Grein, T.; Leitmeyer, K.C.; Mardel, S.; Merianos, A.; Olowokure, B.; Roth, C.; Slattery, R.; Thomson, G.; Werker, D.; Ryan, M. (2004). "The WHO Response to SARS and Preparations for the Future". National Academies Press (US). Retrieved 26 June 2024.
  40. ^ "CDC SARS Response Timeline". CDC. 3 August 2018. Retrieved 26 June 2024.
  41. ^ "Revision of the International Health Regulations Severe acute respiratory syndrome (SARS)" (PDF). World Health Organization. 17 May 2003. Retrieved 26 June 2024.
  42. ^ Shi, Z.; Wang, L.-F. (2017). "Evolution of SARS Coronavirus and the Relevance of Modern Molecular Epidemiology". Genetics and Evolution of Infectious Diseases. Elsevier. pp. 601–619. doi:10.1016/b978-0-12-799942-5.00026-3. ISBN 978-0-12-799942-5.
  43. ^ Koh, D.; Lim, M. K. (1 August 2003). "SARS and occupational health in the air". Occupational and Environmental Medicine. 60 (8): 539–540. doi:10.1136/oem.60.8.539. ISSN 1351-0711. PMC 1740596. PMID 12883012.
  44. ^ "Closure of schools: Joint Press Release by MOE and MOH". NAS. 26 March 2003. Archived from the original on 15 January 2020. Retrieved 15 January 2020.
  45. ^ Li Y, Huang X, Yu IT, Wong TW, Qian H (April 2005). "Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong". Indoor Air. 15 (2): 83–95. Bibcode:2005InAir..15...83L. doi:10.1111/j.1600-0668.2004.00317.x. PMID 15737151. S2CID 43348086.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  46. ^ Severe Acute Respiratory Syndrome – Press briefing Archived 17 April 2003 at the Wayback Machine 1 April 2003 www.who.int. Retrieved 22 January 2020
  47. ^ "Phased Reopening of Schools". NAS. 5 April 2003. Archived from the original on 15 January 2020. Retrieved 15 January 2020.
  48. ^ Keith Bradsher With Lawrence K. Altman: Asian Officials Say Mysterious Disease May Be Here to Stay 9 April 2003 The New York Times. Retrieved 22 January 2020
  49. ^ "Church Member Dies of SARS", 11 April 2003, lds.org. Retrieved 22 January 2020
  50. ^ "Panic as China's SARS toll rises". The Age. 12 April 2003. Archived from the original on 2 June 2017. Retrieved 20 April 2015.
  51. ^ Reported on CBS's The Early Show Tatiana Morales: American Family Affected By SARS 11 April 2003, CBS News. Retrieved 22 January 2020
  52. ^ "American SARS boy back home [SOUTHCN.COM]". newsgd.com. Archived from the original on 3 March 2016. Retrieved 20 April 2015.
  53. ^ "Timeline: SARS outbreak". CNN. 24 April 2003. Archived from the original on 27 April 2015. Retrieved 20 April 2015.
  54. ^ Sars illness 'not under control' Archived 28 June 2003 at the Wayback Machine 11 April 2003, bbc.co.uk. Retrieved 22 January 2020
  55. ^ Scientists claim SARS breakthrough 14 April 2003, Archived from Australian Broadcasting Corporation. Retrieved 22 January 2020
  56. ^ Coronavirus never before seen in humans is the cause of SARS Unprecedented collaboration identifies new pathogen in record time Archived 12 August 2004 at the Wayback Machine Geneva, 16 April 2003, www.who.int. Retrieved 22 January 2020
  57. ^ Singh, Sandeep (1 May 2003). "SARS in India". India: Outlook. Archived from the original on 12 June 2020. Retrieved 7 June 2020.
  58. ^ "Sars spreads to India". The Guardian. 17 April 2003. Archived from the original on 12 June 2020. Retrieved 9 June 2020.
  59. ^ Eckholm, Erik (23 April 2003). "The SARS Epidemic: Beijing; Chinese Capital Closes Schools for at Least Two Weeks". The New York Times. ISSN 0362-4331. Archived from the original on 5 September 2023. Retrieved 5 September 2023.
  60. ^ Rodier, G. R. (2003). "Why was Toronto included in the World Health Organization's SARS-related travel advisory?". Canadian Medical Association Journal. 168 (11): 1434–1435. PMC 155962. PMID 12771075.
  61. ^ Chen, Melody (16 April 2003). "DOH says girl contracted SARS". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  62. ^ Chen, Yun-ping (28 April 2003). "Taipei health chief deflects blame bug". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  63. ^ Chen, Melody (24 April 2003). "New SARS cases linked to hospital". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  64. ^ Chang Yun-ping (25 April 2003). "SARS epidemic: Taipei City closes down hospital". Taipei Times. Archived from the original on 29 January 2020. Retrieved 22 January 2020.
  65. ^ Han Cheung (18 April 2020). "Taiwan in Time: Remembering the SARS lockdown". Taipei Times. Archived from the original on 22 April 2020. Retrieved 19 April 2020.
  66. ^ Toronto travel warning lifted Archived 21 August 2006 at the Wayback Machine 30 April 2003, news.bbc.co.uk. Retrieved 22 January 2020
  67. ^ Cohen, Tom (29 May 2003). "Canada Broadens Definition of SARS Cases". Kansas City Star. Associated Press. Archived from the original on 30 October 2004.
  68. ^ Chuang, Jimmy (24 May 2003). "Hoping investigation now focusing on top officials". Taipei Times. Archived from the original on 16 May 2020. Retrieved 20 April 2020.
  69. ^ "SARS doctors' ethics put to the test". Taipei Times. Reuters. 26 May 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  70. ^ Wu, Debby (27 May 2003). "Hospital officials freed on bail". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  71. ^ Chuang, Jimmy (25 May 2003). "Fate of two Hoping Hospital officials still under review". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  72. ^ Lu, Fiona (28 May 2003). "Control Yuan faults hospital closure". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  73. ^ Wu, Debby; Chen, Melody (26 May 2003). "City health director steps down". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  74. ^ Wu, Debby (25 May 2003). "City health chief comes under fire". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  75. ^ Hsu, Brian (28 May 2003). "Central area unveils new SARS center". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  76. ^ "Ten regional hospitals install SARS-patient facilities". Taipei Times. Central News Agency. 26 May 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  77. ^ Campbell, Archie Gray (15 April 2004). SARS and Public Health in Ontario (Volume 4) (PDF). Toronto: Queen's Printer for Ontario. ISBN 1-4249-2823-0. Archived (PDF) from the original on 24 December 2018. Retrieved 2 May 2020.
  78. ^ a b "WHO to say nation now free of SARS". Taipei Times. 5 July 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  79. ^ "Country counting down to day WHO removes it from list". Taipei Times. 3 July 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  80. ^ "WHO takes Taiwan off SARS list". Taipei Times. 6 July 2003. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  81. ^ Su, Joy (18 December 2003). "Medical researcher contracts SARS". Taipei Times. Archived from the original on 16 May 2020. Retrieved 19 April 2020.
  82. ^ a b Zhang, Feng (2 July 2004). "Officials punished for SARS virus leak". China Daily. Archived from the original on 19 February 2020. Retrieved 14 February 2020.
  83. ^ Stephenson, Joan (2 June 2004). "SARS in China". JAMA. 291 (21): 2534. doi:10.1001/jama.291.21.2534-d.
  84. ^ Liang, WN; et al. (2006). "Severe acute respiratory syndrome – retrospect and lessons of 2004 outbreak in China". Biomed Environ Sci. 19 (6): 445–51. PMID 17319269.
  85. ^ Jim Yardley: After Its Epidemic Arrival, SARS Vanishes Archived 28 January 2020 at the Wayback Machine 15 May 2005 The New York Times. Retrieved 22 January 2020
  86. ^ Heilmann, Sebastian (2018). Red Swan: How Unorthodox Policy-Making Facilitated China's Rise. The Chinese University of Hong Kong Press. doi:10.2307/j.ctv2n7q6b. ISBN 978-962-996-827-4. JSTOR j.ctv2n7q6b. S2CID 158420253.
  87. ^ Zhang, Angela Huyue (2024). High Wire: How China Regulates Big Tech and Governs Its Economy. Oxford University Press. ISBN 9780197682258.

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