Prostaglandin E3 (PGE3) is a naturally formed prostaglandin and is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.[1]

Prostaglandin E3
Clinical data
AHFS/Drugs.comInternational Drug Names
Identifiers
  • (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H30O5
Molar mass350.455 g·mol−1
3D model (JSmol)
  • CC/C=C\C[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O
  • InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h3-4,6-7,12-13,15-17,19,21,23H,2,5,8-11,14H2,1H3,(H,24,25)/b6-3-,7-4-,13-12+/t15-,16+,17+,19+/m0/s1
  • Key:CBOMORHDRONZRN-QLOYDKTKSA-N

See also

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References

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  1. ^ Kulkarni PS, Srinivasan BD (June 1986). "Eicosapentaenoic acid metabolism in human and rabbit anterior uvea". Prostaglandins. 31 (6): 1159–64. doi:10.1016/0090-6980(86)90217-0. PMID 3020617.