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The Pseudomonadales-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] The Pseudomonadales-1 motif often exhibits an apparent sarcin-ricin loop, a type internal loop common in RNA. Pseudomonadales-1 motif RNAs are found in relatively closely related species of Pseudomonadales. Despite this narrow distribution, the Pseudomonadales-1 RNA motif does not exhibit many invariant nucleotide positions, suggesting that it does not need to be highly conserved at the primary sequence level.
| Pseudomonadales-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of Pseudomonadales-1 RNA | |
| Identifiers | |
| Symbol | Pseudomonadales-1 |
| Rfam | RF03046 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
Pseudomonadales-1 RNAs likely function in trans as small RNAs, as no consistent pattern of associated protein-coding genes is observed.
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.