Puiseux may refer to
- Geography
- Puiseux, Ardennes, a French commune in the Ardennes department
- Puiseux, Eure-et-Loir, a French commune in the Eure-et-Loir department
- Science
- Puiseux crater, a crater on the Moon
- Puiseux series, a mathematical series
- Victor Puiseux, a 19th-century French mathematician