1-(2-Pyridinyl)piperazine is a chemical compound and piperazine derivative. Some derivatives of this substance are known to act as potent and selective α2-adrenergic receptor antagonists, such as 1-(3-fluoro-2-pyridinyl)piperazine.[1]
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Preferred IUPAC name
1-(Pyridin-2-yl)piperazine | |
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ECHA InfoCard | 100.047.458 |
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Properties | |
C9H13N3 | |
Molar mass | 163.22 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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A few pyridinylpiperazine derivatives are drugs, including:
- Azaperone — antipsychotic
- Atevirdine — antiretroviral
- Delavirdine — antiretroviral
- Mirtazapine — antidepressant
See also
editReferences
edit- ^ Saari WS, Halczenko W, King SW, et al. (December 1983). "Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists". Journal of Medicinal Chemistry. 26 (12): 1696–701. doi:10.1021/jm00366a007. PMID 6139479.