The Pyrobac-1 RNA motif is a conserved RNA structure discovered by bioinformatics.[1] RNAs conforming to this motif have been found only in Pyrobaculum, a genus of archaea. Instances of the motif are hypothesized to function as non-coding RNAs. The motif has been shown to be part of sRNA202 and sRNA203 canonical and noncanonical pseudouridine guide RNAs (H/ACA RNA) in Pyrobaculum.[2]
| Pyrobac-1 RNA | |
|---|---|
 Consensus secondary structure of Pyrobac-1 RNAs | |
| Identifiers | |
| Symbol | Pyrobac-1 |
| Rfam | RF01722 |
| Other data | |
| RNA type | sRNA |
| Domain(s) | Pyrobaculum |
| PDB structures | PDBe |
References
edit- ^ Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
- ^ Bernick, David L.; Dennis, Patrick P.; Höchsmann, Matthias; Lowe, Todd M. (March 2012). "Discovery of Pyrobaculum small RNA families with atypical pseudouridine guide RNA features". RNA. 18 (3): 402–411. doi:10.1261/rna.031385.111. ISSN 1469-9001. PMC 3285929. PMID 22282340.
External links
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