Pyrogallol 1,2-oxygenase

In enzymology, a pyrogallol 1,2-oxygenase (EC 1.13.11.35) is an enzyme that catalyzes the chemical reaction

pyrogallol 1,2-oxygenase
Identifiers
EC no.1.13.11.35
CAS no.78310-68-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
1,2,3-trihydroxybenzene + O2 (Z)-5-oxohex-2-enedioate

Thus, the two substrates of this enzyme are 1,2,3-trihydroxybenzene and O2, whereas its product is (Z)-5-oxohex-2-enedioate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing). This enzyme is also called pyrogallol 1,2-dioxygenase.

References

edit
  • Groseclose EE, Ribbons DW (1981). "Metabolism of resorcinylic compounds by bacteria: new pathway for resorcinol catabolism in Azotobacter vinelandii". J. Bacteriol. 146 (2): 460–6. PMC 216987. PMID 7217008.