Quinaldate 4-oxidoreductase

In enzymology, a quinaldate 4-oxidoreductase (EC 1.3.99.18) is an enzyme that catalyzes the chemical reaction

quinaldate 4-oxidoreductase
Identifiers
EC no.1.3.99.18
CAS no.149885-77-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
quinaldate + acceptor + H2O kynurenate + reduced acceptor

The 3 substrates of this enzyme are quinaldate, acceptor, and H2O, whereas its two products are kynurenate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating). This enzyme is also called quinaldic acid 4-oxidoreductase.

References

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  • Sauter M, Tshisuaka B, Fetzner S, Lingens F (1993). "Microbial metabolism of quinoline and related compounds. XX Quinaldic acid 4-oxidoreductase from Pseudomonas sp. AK-2 compared to other procaryotic molybdenum-containing hydroxylases". Biol. Chem. Hoppe-Seyler. 374 (11): 1037–46. doi:10.1515/bchm3.1993.374.7-12.1037. PMID 8292263.
  • Fetzner S, Lingens F (1993). "Microbial metabolism of quinoline and related compounds. XVIII Purification and some properties of the molybdenum- and iron-containing quinaldic acid 4-oxidoreductase from Serratia marcescens 2CC-1". Biol. Chem. Hoppe-Seyler. 374 (6): 363–76. doi:10.1515/bchm3.1993.374.1-6.363. PMID 8357532.