Río Segundo may refer to:
- Segundo River, a river in Córdoba Province, Argentina.
- Río Segundo, Córdoba, a city in Córdoba Province, Argentina.
- Río Segundo Department, an administrative division of Córdoba Province, Argentina.
- Río Segundo District, an administrative division of Alajuela (canton), Alajuela Province, Costa Rica.
This disambiguation page lists articles associated with the title Río Segundo.
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