Retinoic acid early transcript 1E (RAET1E) is a cell surface glycoprotein encoded by RAET1E gene located on the chromosome 6.[3] RAET1E is related to MHC class I molecules, but its gene maps outside the MHC locus.[3] RAET1E is composed of external α1α2 domain, transmembrane segment and C-terminal cytoplasmic tail.[3][4] RAET1E functions as a stress-induced ligand for NKG2D receptor.[4]

RAET1E
Identifiers
AliasesRAET1E, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4, bA350J20.7, retinoic acid early transcript 1E
External IDsOMIM: 609243; HomoloGene: 131086; GeneCards: RAET1E; OMA:RAET1E - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

RefSeq (protein)

NP_001230254
NP_001230256
NP_001230257
NP_631904

n/a

Location (UCSC)Chr 6: 149.88 – 149.9 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164520Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b c Radosavljevic M, Cuillerier B, Wilson MJ, Clément O, Wicker S, Gilfillan S, Beck S, Trowsdale J, Bahram S (Jan 2002). "A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3". Genomics. 79 (1): 114–23. doi:10.1006/geno.2001.6673. PMID 11827464.
  4. ^ a b Jan Chalupny, N; Sutherland, Claire L; Lawrence, William A; Rein-Weston, Annie; Cosman, David (2003-05-23). "ULBP4 is a novel ligand for human NKG2D". Biochemical and Biophysical Research Communications. 305 (1): 129–135. doi:10.1016/S0006-291X(03)00714-9. PMID 12732206.

Further reading

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