The RFamide peptide family, or the RFamide-related peptides (RFRPs), are a family of neuropeptides.[1][2] They are characterized by the possession of an Arg-Phe-NH2 motif at their C-terminal extremities.[1][2]
Members of the family include:[1][2]
- Neuropeptide FF group
- Neuropeptide AF
- Neuropeptide FF
- Neuropeptide SF (RFRP-1)
- Neuropeptide VF (RFRP-3) (GnIH - avian species)
- Prolactin-releasing peptide (PrRP)
- Pyroglutamylated RFamide peptide (QRFP)
- Kisspeptin (disputed)[3]
See also
editReferences
edit- ^ a b c Abba Kastin; Abba J. Kastin (28 April 2011). Handbook of Biologically Active Peptides. Academic Press. pp. 779–. ISBN 978-0-08-046379-7.
- ^ a b c Findeisen, Maria; Rathmann, Daniel; Beck-Sickinger, Annette G. (2011). "RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential". Pharmaceuticals. 4 (9): 1248–1280. doi:10.3390/ph4091248. ISSN 1424-8247. PMC 4058657.
- ^ Yun S, Kim DK, Furlong M, Hwang JI, Vaudry H, Seong JY (2014). "Does Kisspeptin Belong to the Proposed RF-Amide Peptide Family?". Front Endocrinol (Lausanne). 5: 134. doi:10.3389/fendo.2014.00134. PMC 4131245. PMID 25165463.
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