RHOXF1

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Rhox homeobox family member 1 is a protein that in humans is encoded by the RHOXF1 gene.^[3]^[4]^[5]

RHOXF1

Identifiers

RHOXF1, OTEX, PEPP1, Rhox homeobox family member 1

External IDs

OMIM: 300446; HomoloGene: 64643; GeneCards: RHOXF1; OMA:RHOXF1 - orthologs

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	Xq24	Start	120,109,051 bp^[1]
Band	Xq24	End	120,115,913 bp^[1]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

gonad

testicle

right testis

left testis

right hemisphere of cerebellum

right uterine tube

granulocyte

right ovary

right frontal lobe

left ovary

n/a

More reference expression data


More reference expression data

Gene ontology
Molecular function	DNA-binding transcription factor activity DNA binding sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding
Cellular component	nucleus
Biological process	multicellular organism development gamete generation regulation of transcription, DNA-templated intracellular steroid hormone receptor signaling pathway sexual reproduction transcription, DNA-templated positive regulation of gene expression regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO

Species

Human

Mouse


158800


n/a


ENSG00000101883


n/a


Q8NHV9


n/a

RefSeq (mRNA)


NM_139282


n/a

RefSeq (protein)


NP_644811


n/a

Location (UCSC)

Chr X: 120.11 – 120.12 Mb

n/a

PubMed search

^[2]

n/a

View/Edit Human

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101883 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Geserick C, Weiss B, Schleuning WD, Haendler B (Aug 2002). "OTEX, an androgen-regulated human member of the paired-like class of homeobox genes". Biochem J. 366 (Pt 1): 367–75. doi:10.1042/BJ20020399. PMC 1222745. PMID 11980563.
^ Wayne CM, MacLean JA, Cornwall G, Wilkinson MF (Dec 2002). "Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis". Gene. 301 (1–2): 1–11. doi:10.1016/S0378-1119(02)01087-9. PMID 12490318.
^ "Entrez Gene: OTEX paired-like homeobox protein OTEX".

Further reading

Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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