RNR2 (RNA, ribosomal 45S cluster 2[2]) is a human ribosomal DNA gene located on Chromosome 14. Tandem copies of this gene form one of five nucleolus organizer regions in the human genome, they are located on the chromosomes 13 (RNR1), 14 (RNR2), 15 (RNR3), 21 (RNR4), 22 (RNR5).[3][2] Each gene cluster contains 30–40 copies and encodes a 45S RNA product that is then processed to form 18S, 5.8S and 28S rRNA.[2]
| RNR2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | RNR2, RNA, ribosomal 45S cluster 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 180451; GeneCards: RNR2; OMA:RNR2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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References
edit- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b c "Entrez Gene: RNR1 RNA, ribosomal 1". Retrieved 2024-08-01.
- ^ Schmidt, Olaf (2017). Fritsche, Olaf (ed.). Genetik und Molekularbiologie [Genetics and molecular biology]. Kompaktwissen Biologie (in German). Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. doi:10.1007/978-3-662-50274-7. ISBN 978-3-662-50273-0.
Further reading
edit- Nucleolus organizer regions are chromosomal regions crucial for the formation of the nucleolus, located on the short arms of the acrocentric chromosomes 13, 14, 15, 21 and 22
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