RPS27L

Ribosomal protein S27 like is a protein that in humans is encoded by the RPS27L gene.

RPS27L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0
Identifiers
Aliases	RPS27L, ribosomal protein S27 like
External IDs	OMIM: 612055; MGI: 1915191; HomoloGene: 69197; GeneCards: RPS27L; OMA:RPS27L - orthologs
Gene location (Human) Chr. Chromosome 15 (human) Band 15q22.2 Start 63,125,872 bp End 63,158,021 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 C Start 66,853,368 bp End 66,856,798 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in seminal vesicula Epithelium of choroid plexus jejunal mucosa palpebral conjunctiva parotid gland kidney tubule mucosa of sigmoid colon right adrenal cortex body of pancreas tail of epididymis Top expressed in embryo endocardial cushion embryo parotid gland right kidney seminal vesicula lacrimal gland epiblast yolk sac zygote More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of ribosome translation activator activity cysteine-type endopeptidase activator activity involved in apoptotic process protein binding metal ion binding RNA binding Cellular component cytosolic small ribosomal subunit ribosome intracellular anatomical structure nucleus Biological process ribosomal small subunit assembly intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator mitotic G1 DNA damage checkpoint signaling DNA repair protein biosynthesis activation of cysteine-type endopeptidase activity involved in apoptotic process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator positive regulation of translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51065 67941 Ensembl ENSG00000185088 ENSMUSG00000036781 UniProt Q71UM5 Q6ZWY3 RefSeq (mRNA) NM_015920 NM_026467 NM_001311101 NM_001361106 RefSeq (protein) NP_057004 NP_001298030 NP_080743 NP_001348035 Location (UCSC) Chr 15: 63.13 – 63.16 Mb Chr 9: 66.85 – 66.86 Mb PubMed search
Wikidata
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Function

This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008].

Further reading

• Huang CJ, Yang SH, Lee CL, Cheng YC, Tai SY, Chien CC (2013). "Ribosomal protein S27-like in colorectal cancer: a candidate for predicting prognoses". PLOS ONE. 8 (6): e67043. Bibcode:2013PLoSO...867043H. doi:10.1371/journal.pone.0067043. PMC 3691124. PMID 23826192.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.