RUNDC3A

RUN domain-containing protein 3A is a protein that in humans is encoded by the RUNDC3A gene.

RUNDC3A
Identifiers
Aliases	RUNDC3A, RAP2IP, RPIP-8, RPIP8, RUN domain containing 3A
External IDs	OMIM: 605448; MGI: 1858752; HomoloGene: 4871; GeneCards: RUNDC3A; OMA:RUNDC3A - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q21.31 Start 44,308,413 bp End 44,318,670 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 D Start 102,284,229 bp End 102,293,381 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right frontal lobe right hemisphere of cerebellum cingulate gyrus anterior cingulate cortex prefrontal cortex Brodmann area 9 amygdala nucleus accumbens caudate nucleus hippocampus proper Top expressed in neural layer of retina superior frontal gyrus dentate gyrus of hippocampal formation granule cell primary visual cortex cerebellar cortex entorhinal cortex perirhinal cortex CA3 field primary motor cortex lobe of cerebellum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding guanylate cyclase activator activity GTPase regulator activity peptide hormone receptor binding Cellular component cytosol plasma membrane Biological process small GTPase mediated signal transduction positive regulation of guanylate cyclase activity regulation of catalytic activity positive regulation of cGMP-mediated signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10900 51799 Ensembl ENSG00000108309 ENSMUSG00000006575 UniProt Q59EK9 O08576 RefSeq (mRNA) NM_001144825 NM_001144826 NM_006695 NM_001252347 NM_016759 NM_001362803 NM_001362804 RefSeq (protein) NP_001138297 NP_001138298 NP_006686 NP_001239276 NP_058039 NP_001349732 NP_001349733 Location (UCSC) Chr 17: 44.31 – 44.32 Mb Chr 11: 102.28 – 102.29 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Interactions

RUNDC3A has been shown to interact with RAP2A.

See also

• RUN domain

Further reading

• Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.