Redox-regulatory protein FAM213A

Redox-regulatory protein FAM213A also known as peroxiredoxin-like 2 activated in M-CSF stimulated monocytes (PAMM) is a protein that in humans is encoded by the FAM213A gene.

PRXL2A
Identifiers
Aliases	PRXL2A, C10orf58, PAMM, family with sequence similarity 213 member A, Adrx, FAM213A, peroxiredoxin like 2A
External IDs	OMIM: 617165; MGI: 1917814; HomoloGene: 12356; GeneCards: PRXL2A; OMA:PRXL2A - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q23.1 Start 80,407,829 bp End 80,437,115 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 B Start 40,715,697 bp End 40,735,745 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium corpus epididymis myocardium of left ventricle skin of thigh mucosa of ileum jejunal mucosa skin of arm caput epididymis skin of hip vulva Top expressed in retinal pigment epithelium blood utricle tunica adventitia of aorta ciliary body brown adipose tissue Epithelium of choroid plexus white adipose tissue vestibular sensory epithelium dorsomedial hypothalamic nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function antioxidant activity Cellular component cytoplasm extracellular region Biological process regulation of osteoclast differentiation cellular oxidant detoxification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84293 70564 Ensembl ENSG00000122378 ENSMUSG00000021792 UniProt Q9BRX8 Q9CYH2 RefSeq (mRNA) NM_001243778 NM_001243779 NM_001243780 NM_001243781 NM_001243782 NM_032333 NM_027464 NM_001316732 NM_001316733 NM_001316734 NM_001316735 NM_001316736 NM_001316737 NM_001316739 NM_001316740 NM_001378813 NM_001378814 NM_001378815 RefSeq (protein) NP_001230707 NP_001230708 NP_001230709 NP_001230710 NP_001230711 NP_115709 NP_001303661 NP_001303662 NP_001303663 NP_001303664 NP_001303665 NP_001303666 NP_001303668 NP_001303669 NP_081740 NP_001365742 NP_001365743 NP_001365744 Location (UCSC) Chr 10: 80.41 – 80.44 Mb Chr 14: 40.72 – 40.74 Mb PubMed search
Wikidata
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Further reading

• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.