In enzymology, a ribitol-5-phosphate 2-dehydrogenase (EC 1.1.1.137) is an enzyme that catalyzes the chemical reaction
| ribitol-5-phosphate 2-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.137 | ||||||||
| CAS no. | 37250-67-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- D-ribitol 5-phosphate + NAD(P)+ D-ribulose 5-phosphate + NAD(P)H + H+
The 3 substrates of this enzyme are D-ribitol 5-phosphate, NAD+, and NADP+, whereas its 4 products are D-ribulose 5-phosphate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase. This enzyme is also called dehydrogenase, ribitol 5-phosphate. This enzyme participates in pentose and glucuronate interconversions.
References
edit- Glaser L (April 1963). "Ribitol-5-phosphate dehydrogenase from Lactobacillus plantarum". Biochimica et Biophysica Acta. 67: 525–30. doi:10.1016/0006-3002(63)91863-8. PMID 13948358.
