Ring finger protein 157

Ring finger protein 157 is a protein that in humans is encoded by the RNF157 gene.

RNF157
Identifiers
Aliases	RNF157, ring finger protein 157
External IDs	MGI: 2442484; HomoloGene: 28235; GeneCards: RNF157; OMA:RNF157 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q25.1 Start 76,142,465 bp End 76,240,493 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 E2 Start 116,227,179 bp End 116,303,858 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lateral nuclear group of thalamus right frontal lobe cingulate gyrus anterior cingulate cortex dorsolateral prefrontal cortex Brodmann area 9 pars compacta prefrontal cortex pars reticulata gastrocnemius muscle Top expressed in motor neuron facial motor nucleus trigeminal ganglion substantia nigra dentate gyrus of hippocampal formation granule cell Region I of hippocampus proper superior frontal gyrus visual cortex primary visual cortex retinal pigment epithelium More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding transferase activity ubiquitin protein ligase activity Cellular component cytoplasm cell body Biological process protein ubiquitination negative regulation of apoptotic process protein autoubiquitination positive regulation of dendrite extension Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114804 217340 Ensembl ENSG00000141576 ENSMUSG00000052949 UniProt Q96PX1 Q3TEL6 RefSeq (mRNA) NM_052916 NM_001330501 NM_027258 RefSeq (protein) NP_001317430 NP_443148 n/a Location (UCSC) Chr 17: 76.14 – 76.24 Mb Chr 11: 116.23 – 116.3 Mb PubMed search
Wikidata
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Further reading

• Talmud PJ, et al. (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
• Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A (December 2010). "Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study". Mutat. Res. 694 (1–2): 13–9. doi:10.1016/j.mrfmmm.2010.08.006. PMID 20800603.