Ruffer is an English surname. Notable people with the surname include:
- Jonathan Ruffer (born 1951), British fund manager and philanthropist
- Marc Armand Ruffer (1859–1917), Swiss-born English experimental pathologist
- Maurice Ruffer (1857–1935), French-born British banker
- Corinna Rüffer (born 1975), German politician
See also
edit- Ruffer Investment Company, investment company listed on the London Stock Exchange
- A Ruffer & Sons, defunct family bank