Rutherglen is a town in South Lanarkshire, Scotland that has existed for over 800 years.
Rutherglen may also refer to:
- Rutherglen, Glasgow, a royal burgh in the unitary authority of South Lanarkshire in Scotland
- Rutherglen railway station
- Rutherglen (UK Parliament constituency) parliamentary constituency from 1918 to 2005
- Rutherglen High School
- Rutherglen, Victoria, a small town in Australia, named after the Scottish burgh
- Rutherglen, Ontario, a community in Bonfield, Canada