SAICA may refer to:
- South African Institute of Chartered Accountants, a non-profit association
- Sociedades anónimas inscrito de capital abierto, a type of companies in Argentina
- Succinylaminoimidazolecarboxamide riboside (SAICA riboside), a molecule whose appearance is characteristic of the disease adenylosuccinate lyase deficiency
Saica may refer to:
- Saica (bug), a genus of bugs in the family Reduviidae